If you mix two powders together, they will not react with each other very quickly. This is why almost all organic chemistry is done in solution. Once the reaction is complete, the solvent must be removed. This is most often done with a machine called a rotary evaporator. It contains a vacuum pump that lowers the boiling point of the solvent. The solvent evaporates and is caught in a condenser before it can reach the pump. Some solvents require a liquid nitrogen cold trap because they have such a low boiling point and high vapor pressure that without extreme measures, they would get past the condenser into the vacuum pump and contaminate the pump oil.
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